By H. Lassmann

For numerous a long time the unsolved etiogenetic and healing difficulties of a number of sclerosis have provided the most powerful problem to investigate in neu­ rology. The desire of decisive theoretical and sensible development elevated whilst an experimental version proposing far-reaching conformity of structural and pathogenetic positive aspects used to be constructed, particularly power re­ lapsing experimental allergic encephalomyelitis (CREAE). prior to now years, Dr. Lassmann has contributed considerably to the variation of this version with the purpose of complete review, completely fol­ lowing up his personal principles in different stories of person points. the hot hazard of non-stop and distinctive research of the scientific, morphological and immunological features of temporal section series of autoimmune demyelination has ended in many new findings, corrections offormer hypotheses, and, from correlated experiences of human a number of sclerosis, a chain of significant information bearing on, for instance, early manifestations of demyelination, the variety of so-called acute mul­ tiple sclerosis and the occurrence of remyelination. furthermore, Dr. Lass­ mann has analysed a number of particular difficulties which turned definable during his personal reports or in collaboration with different teams, in­ cluding the preliminary distribution of demyelinated foci, the cerebrospinal fluid phenomena and immunological findings within the worried tissue. the result of those separate reports additionally ended in a deeper realizing of demyelinating methods. This monograph integrates those stories and summarizes their re­ sults.

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Comparative Neuropathology of Chronic Experimental Allergic Encephalomyelitis and Multiple Sclerosis (Schriftenreihe Neurologie Neurology Series) by H. Lassmann


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